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270 BCE
260 BCE
250 BCE
240 BCE
230 BCE
220 BCE
210 BCE
200 BCE
190 BCE
180 BCE
170 BCE
160 BCE
150 BCE
264 BCE - 241 BCE: First Punic War. Carthage cedes Sicily to Rome.
237 BCE: Hamilcar Barca arrives in southern Spain to expand Carthage's interests there. He makes his base at Gades and founds Acra Leuce.
229 BCE: Hasdrubal takes command of Carthage's armies in Spain.
226 BCE: Hasdrubal signs an agreement with Rome not to cross the Ebro river in Spain.
221 BCE: Hannibal takes command of Carthage's armies in Spain.
219 BCE: Hannibal crosses the Ebro river in Spain and sacks the city of Saguntum, Rome's ally, sparking off the Second Punic War.
218 BCE - 201 BCE: Second Punic War.
218 BCE: Scipio Africanus lands an army at Empuries in northeastern Spain during the Second Punic War.
218 BCE: Rome declares war on Carthage after Hannibal sacks Saguntum in Spain. The Second Punic War begins.
218 BCE: Hannibal leaves Spain to cross the Pyrenees and Alps into Italy.
218 BCE: Hannibal wins the battle of Ticinus.
218 BCE: Hannibal wins the battle of Trebia.
217 BCE: Hannibal wins the battle of Lake Trasimene.
216 BCE: Marcus Claudius Marcellus successfully defends Nola against attack from Hannibal during the Second Punic War.
216 BCE: "Hannibal ante portas." Hannibal directly threatens the city of Rome, but cannot advance due to lack of supplies and reinforcements.
216 BCE: Hannibal wins the battle of Cannae, the worst defeat in Roman history.
215 BCE: A Carthaginian army led by Hasdrubal is defeated at the battle of Ibera in Spain.
214 BCE: Syracuse joins the side of Carthage in the Second Punic War.
213 BCE - 212 BCE: Roman commander Marcus Claudius Marcellus lays seige to and ultimately sacks Syracuse.
212 BCE: A Carthaginian army is defeated in Sicily by a Roman army led by Marcellus. Syracuse falls to Rome who now control the island.
211 BCE: Marcus Claudius Marcellus is given a triumph for his capture of Syracuse and victories in Sicily.
211 BCE: Scipio Africanus lands an army for the second time at Empuries in northeastern Spain during the Second Punic War.
211 BCE: A Carthaginian army defeats two Roman consuls and their armies in the Tader valley, Spain.
210 BCE - 207 BCE: Scipio Africanus conquers Spain for Rome.
209 BCE: Tarentum comes under Roman control during the Second Punic War.
209 BCE: Scipio Africanus captures the Carthaginian base and treasury Carthago Nova in southern Spain.
208 BCE: Roman commander Marcus Claudius Marcellus is killed in an ambush in Venusia, southern Italy.
208 BCE: Scipio Africanus defeats a Carthaginian army led by Hasdrubal at Baecula in Spain.
207 BCE: Hannibal, harassed by Roman forces, is reduced to controlling only Bruttium in southern Italy.
207 BCE: Rome defeats a Carthaginian army at the battle of Metaurus.
206 BCE: Massinissa of Numidia betrays Carthage and joins forces with the Roman Republic.
206 BCE - 205 BCE: The Romans conquer Gades. End of the Carthaginian presence on the Iberian Peninsula.
206 BCE: Scipio Africanus wins the battle of Ilipa in Spain.
204 BCE - 203 BCE: Scipio Africanus wins two battles and besieges Utica in North Africa.
204 BCE: Scipio Africanus sails to North Africa in the Second Punic War.
203 BCE: Carthaginian commander Mago is unable to join forces with Hannibal and his army is defeated in Cisalpine Gaul.
203 BCE: Scipio Africanus attacks the two camps of Syphax and Gisgo in North Africa and destroys their armies.
203 BCE: Scipio Africanus defeats a Carthaginian army led by Hasdrubal in North Africa.
203 BCE: Hannibal is recalled from Italy to defend Carthage against Scipio Africanus.
202 BCE: Battle of Zama: Scipio Africanus defeats Hannibal, ending the Second Punic War.
149 BCE - 146 BCE: Third Punic War.